May River Rd Homes for Sale

Welcome to May River Road in the charming town of Bluffton, South Carolina! Nestled in the heart of Beaufort County, this picturesque subdivision offers a blend of southern charm and modern living, making it a perfect place to call home. With its serene landscapes, lush greenery, and the tranquil waters of the May River nearby, residents enjoy a peaceful lifestyle that’s just a stone’s throw away from the vibrant culture and amenities of the Lowcountry.

Homes for sale in the May River Road area showcase a variety of architectural styles, from classic Lowcountry designs to contemporary builds that cater to a range of preferences and budgets. Whether you’re searching for a cozy cottage or a spacious family home, you’ll find properties that boast open floor plans, gourmet kitchens, and expansive outdoor spaces ideal for entertaining or simply relaxing in the warm southern sun.

The community is not just about beautiful homes; it’s also about lifestyle. Residents here enjoy easy access to outdoor activities, including boating, fishing, and hiking, thanks to the nearby May River and numerous parks. Bluffton’s charming Old Town, with its eclectic shops, delightful eateries, and vibrant art scene, is only a short drive away, offering a perfect blend of leisure and culture.

If you’re looking for a place that embodies the beauty of the Lowcountry while providing a welcoming community atmosphere, May River Road is an exceptional choice. Explore the homes for sale today and discover the perfect backdrop for your next chapter in this enchanting part of South Carolina!

Newest May River Rd Homes for Sale

$6,985,000

5 Beds ⋅ 5 Baths ⋅ HILTONHEAD-504994 MLS

One of the last remaining legacy waterfront estates in Bluffton, this extraordinary property is being offered for the first time in 65 years. Encompassing 16.6 acres of high ground adorned with majestic trees and heirloom plantings, the estate boasts 485 feet of frontage along the scenic May River, with sweeping views both upriver and downriver. Accessed from picturesque South Carolina Highway 46, the property enjoys a prime location just minutes from downtown Bluffton, approximately 20 minutes to historic Savannah, and 30 minutes to charming Beaufort. The existing approximately 3,400-square-foot residence, built in the 1960s, offers the opportunity for restoration or the perfect footprint for a custom new build. A private dock and swimming pool enhance the waterfront lifestyle, while rare Old Line Camellia plantings add character and timeless Southern charm. With substantial acreage between May River Road and the riverfront, the estate offers exceptional privacy and flexibility-ideal for a multigenerational family compound, equestrian retreat, or legacy waterfront residence. A rare opportunity to secure one of Bluffton's most significant remaining riverfront properties.

942 May River Road, Bluffton

Listing courtesy of Charter One Realty.

Start Your Search

We do not attempt to independently verify the currency, completeness, accuracy or authenticity of the data contained herein. It may be subject to transcription and transmission errors. Accordingly, the data is provided on an “as is” “as available” basis only and may not reflect all real estate activity in the market. © 2026 REsides, Inc. All rights reserved. Certain information contained herein is derived from information, which is the licensed property of, and copyrighted by, REsides, Inc.